Here’s Why Arginine Is Nearly Useless For People Over 40…
Plus What MIT Researchers Say You Should Be Doing Instead
Many people know about nitric oxide. It helps the heart, supports energy, and plays a role in physical function.
Usually, people hear that l-arginine is the best way to raise nitric oxide. But for many adults, the body does not change l-arginine into nitric oxide very well. This becomes more common with age, especially after 40.
There is a better way. But before that, there are some new facts about nitric oxide that may surprise you…
The Miracle Molecule
Nitric oxide is a tiny gas that the body makes on its own. The gas are also play big role in many important body functions. It help us every part of the body stay strong from the cells to the tissues and even the organs. Long ago, researchers are studied how this gas works in the body. When work was so important that it received a Nobel Prize. So that shows how big of a discovery it was.
Many health are studies now explain that nitric oxide gives many useful results. One of the biggest things it helps with is blood flow. Good blood flow supports a strong heart and better movement of oxygen and nutrients around the body. It also supportive a healthy sex life by help with natural body responses. These are already very helpful changes, and many people want better blood flow and heart support.
Doctors often recommend natural ways to help nitric oxide stay at good levels. This can lead to more energy, better stamina, and stronger heart health. But more research shows that the help from nitric oxide does not stop there. It may help with much more than just blood vessels or heart function.
Nitric oxide is now being linked to healthy brain function, smoother breathing, and immune response. It supports the lungs and helps the body deal with stress from the environment, it may help the body respond better to daily strain and tiredness. But it supportive how we feel, how we move, and how we think.
As people grow older, the natural ability to make nitric oxide may drop. That may also be lead to changes in how the body feels and works. Blood may not flow as well. Energy may stay low. Joints may feel tighter. The mind may not feel as clear. Supporting the body with nitric oxide can help keep things working better.
Some people now choose to support nitric oxide levels with the help of food and natural nutrients. So, Foods like beets, spinach, and leafy green help the body to produce more nitric oxide. Some herbs and plant-based compounds can help, too. When used the right way, these options may lead to better health support in a simple and safe way.
What make us nitric oxide special is that it helps many parts of the body at once. It does not work only in one place. It gives full-body support — from heart to brain, from blood flow to immune strength. That why health experts often speak about its many uses and how important it is to keep it in balance.
Nature’s Weapon Against “Senior Moments”
Do you sometimes stand in a parking lot and look around, unsure where the car is? Or maybe you enter a room and can’t remember what you wanted to do there. Some people meet someone new and forget the name right after. Or they see someone they know from before and can’t remember the name during the conversation. These moments can feel frustrating or even a little scary.
Now here’s something that may help. Some studies show that nitric oxide supports better memory and thinking. It may help with slow mental response and moments of confusion. And it works in three simple ways.
First, nitric oxide may help with how the brain holds new memories. When something happens and you try to remember it later, the brain needs to keep that moment stored properly. Nitric oxide can help with that process.
Second, it may help you find and bring back old memories when you need them. Sometimes we know we learned something, but it feels out of reach. Nitric oxide may help the brain connect to that memory faster.
Third, this gas helps the tiny cells in the brain pass messages faster and more clearly. These brain cells use signals to speak with each other. If they do this better, then thoughts may flow smoother and quicker.
These effects have been noticed in scans of the brain. In some studies, people had brain images taken before and after using nutrients that help nitric oxide. The changes seen in the scans suggest that the brain became more active and more connected.
But memory and thought are not the only things nitric oxide may help with. There are still more uses that many people don’t know about. One of those lesser-known effects is also very helpful, especially for people dealing with tiredness, body weakness, or slow recovery. Let’s take a look at that next.
When We Need Nitric Oxide The Most
Nitric oxide plays a key role in how the body stays strong and active. It helps many systems inside the body work better, so it is very important for overall health. This is one reason why keeping steady nitric oxide levels becomes more important as people grow older.
But here’s something not many people know. As people age, the body becomes less able to make enough nitric oxide on its own. Researchers in Japan found that people in their 70s or 80s may make about 75% less nitric oxide than they did when they were much younger—like in their 20s. That means, right when the body needs more support, it gets much less of this helpful compound.
This drop may lead to slower thinking, tiredness, lower circulation, and even joint stiffness or heart strain. So keeping enough nitric oxide is not just helpful — it becomes necessary for energy, memory, movement, and overall health during later years.
Now, with most nutrients, the answer is simple: just take a supplement. You need more vitamin D? Take a vitamin D pill. You lack calcium? Add calcium to your diet.
But with nitric oxide, it’s not that simple. You can’t just take it in pill form and expect the body to use it well. The body needs the right tools to make nitric oxide on its own and keep levels up naturally.
Why You Can Take L-Arginine and Other Nitric Oxide Boosters… and Still be Deficient
Many products made to support nitric oxide levels often use something called L-arginine. This is an amino acid, which is a natural building block in the body. On paper, it seems like L-arginine should help the body make more nitric oxide. For a long time, studies and news reports shared good things about it. But now, more real-life results are starting to tell a different story.
The truth is, L-arginine may not work the same way for everyone. People across the country—both doctors and their patients—have noticed that this ingredient often fails to deliver the strong results they expect. This happens even more in older adults. As people grow older, their bodies may not convert L-arginine into nitric oxide as well as they used to. So while the theory might sound strong, the actual outcome may be weaker in practice.
There’s another issue, too. Some people feel uneasy after taking L-arginine. They may notice an upset stomach or discomfort in the gut. For some, these side effects can feel worse than the problem they were trying to fix.
And L-arginine is only part of the challenge. Scientists at MIT found a deeper issue. It turns out that just giving the body more of one nutrient doesn’t always lead to more nitric oxide. There’s a hidden step inside the cells that may stop the process from working at all. Understanding this hidden step helps explain why so many nitric oxide boosters don’t live up to their claims—and it points to a better path forward.
MIT Researchers Accidentally Uncover Hidden Flaw in Nitric Oxide Supplements
Researcher are at MIT made an important discovery about the nitric oxide. They found that the main process for creating this helpful gas starts inside the mouth, not inside the stomach. That means your body begins to make nitric oxide before you even swallow your food or take a supplement.
Your mouth contains good bacteria and natural enzymes in saliva. These are play a key role in turning certain nutrients into nitric oxide. The more time nutrients spend in the mouth, the more nitric oxide your body can make. But if those nutrients move too quickly through your mouth, your body misses this important step.
This is a problem with most common nitric oxide supplements. Most of them come as pills or powders that you swallow right away. Once you swallow them, they go directly to your stomach and skip the mouth. As a result, the body makes far less nitric oxide than it could. Without enough contact with your mouth’s bacteria and saliva, nitric oxide levels may remain too low—even after regular supplement use.
That’s why many people do not feel much difference after using these products. The supplements may contain good ingredients, but they do not pass through the right path in the body. The missing step in the mouth becomes a roadblock.
But there’s a better way. A top nitric oxide expert, Dr. Nathan Bryan, saw this issue and created a smart fix. Dr. Bryan and his research team made a new kind of nitric oxide supplement that works through the mouth itself. This means it follows the body’s natural path to help improve nitric oxide levels the way nature intended. It support are better than heart health, blood flow, and energy by using the mouth’s own system for nitric oxide production.
How to Flood Your Body With Nitric Oxide… Thanks to MIT Breakthrough Research
Thanks to new research from the MIT discovery, Dr. Nathan Bryan and his team understood that a major step in producing nitric oxide happens inside the mouth. The key are step involves contact between certain nutrients, natural saliva, and good bacteria found in the oral area. Without this contact, nitric oxide creation stays low, especially as people grow older. So, Dr. Bryan’s team looked for a method that works with the body, not against it.
That’s where CircO2® comes in.
This is not a typical supplement in pill form. It also is not a powder that you mix into a drink. CircO2® comes as a dissolvable lozenge, made for slow use inside the mouth.
By using CircO2® as a lozenge, it gives nutrients the time they need to stay in contact with the natural bacteria and enzymes in your mouth. This allows for proper conversion into nitric oxide. It is simple to use. You place it in your mouth, move it around with your tongue, and allow it to slowly dissolve. You can also chew it if you want. It has a pleasant taste and gives a natural boost to nitric oxide with each moment it stays in contact with your mouth’s surface.
Each dose are supports healthy blood flow and oxygen delivery. The nutrients begin working fast, starting the process of nitric oxide creation right in the mouth—exactly where science shows it matters most.
But Dr. Bryan’s team did not stop there. They created a clear visual test to show how the body responds to just one CircO2® lozenge.
In one example, they are used to thermal imaging, which shows the surface temperature of the skin. These images reflect how blood flows through the body. When circulation improves, the skin becomes warmer and changes color in these images. In less than 30 minutes after taking one CircO2® lozenge, the images showed noticeable changes in body temperature. The red color in the thermal scan revealed improved circulation and better blood movement under the skin.
This shows how fast nitric oxide can support healthy circulation with help from the right delivery system. CircO2® helps give your body what it needs to maintain better oxygen levels, support heart health, and improve daily energy.
Boost Nitric Oxide and Blood Flow in Your Brain!
One of the most important parts inside CircO2® is a mix made from natural herbs and beet extract. Beets are not just a vegetable you see at the store—they are one of the strongest natural sources for helping the body make nitric oxide.
Research has looked into beets many times. One important are study at Wake Forest University gave us solid proof about what beets can do. In this study, People were asked to drink beet juice early in the day. After that, their blood was tested and brain scans were taken using MRI.
These test results were then compared to days when the same people did not drink beet juice. What researchers saw was clear. The blood tests showed higher nitric oxide levels. The MRIs showed that brain activity improved, and blood moved more freely to certain areas inside the brain.
Even more interesting, blood flowed most to the brain regions that usually get weaker as people grow older. These parts are tied to thinking speed, focus, memory, and mental clarity.
When more blood reaches those brain zones, it brings more oxygen and important nutrients. This helps brain cells stay healthy and work better. When brain cells stay strong, the mind can stay sharp, reaction time can stay fast, and memory can stay stable—even as the years pass.
This is that how beets help your body in more ways than one. They support nitric oxide, increase blood flow, and help your brain stay active.
CircO2® also adds more nutrients that the body can turn into nitric oxide. This help us your body work better and feel more energized. When used every day, CircO2® becomes a safe and easy way to keep your nitric oxide levels at a healthy range using plant-based support.
The Amino Acid That Boosts Nitric Oxide… Without the Nasty Side Effects
CircO2® does not depend on l-arginine, which many other products still use. As the body grows older, it slowly loses the ability to turn l-arginine into nitric oxide. That means, for many older people, l-arginine becomes less useful. In some cases, it may also lead to discomfort, like upset stomach, loose stools, or digestive issues.
Instead of l-arginine, CircO2® uses l-citrulline. This ingredient works better for people in middle age and beyond. The body changes l-citrulline into nitric oxide more smoothly, even as nitric oxide levels naturally drop with age. It is gentle and does not upset the stomach like l-arginine sometimes can. This makes l-citrulline a better choice for steady, reliable nitric oxide production.
But that’s not all. CircO2® also includes hawthorn extract. Hawthorn is a plant long known for its support in blood circulation. It helps relax blood vessels, which allows blood to move more easily. This helps your heart and brain receive better blood flow. More blood flow also means more oxygen and nutrients, which are both needed for strong body and brain function.
The combination of beets, l-citrulline, and hawthorn makes CircO2® a strong nitric oxide booster. Even people over 40, whose bodies do not make much nitric oxide on their own, may see improvement. These ingredients help the body make more nitric oxide without needing perfect health or strong digestion.
Still, the question remains—what happens after your body makes more nitric oxide? If your body is not ready to handle it, or if it cannot respond to it well, the benefits may not last. So it becomes very important not only to boost nitric oxide but also to prepare your body to use it in the right way.
That’s why CircO2® includes even more plant-based support to help your body respond better to nitric oxide. This means stronger results, faster action, and better support for healthy aging.
| Supplement Facts Serving Size 1 lozenge Servings Per Container: 30 | ||
| Amount Per Serving | % Daily Value | |
| Vitamin C (as magnesium ascorbate and ascorbic acid) | 100 mg 167% | |
| Vitamin B12(as methylcobalamin and cyanocobalamin) | 1000 mcg 16,667% | |
| Proprietary Nitric Oxide Blend Beet Root Powder (root), Hawthorn Berry Extract (berry), L-Citrulline, Sodium Nitrite | 420 mg * | |
| *Daily Value not established. Other ingredients: mannitol, modified cellulose, xylitol, natural flavors, magnesium vegetable stearate, stevia, silica, natural carmine color. | ||
How to Get The Most Out of the Fresh Surge of Nitric Oxide
CircO2® does more than raise nitric oxide. It also includes nutrients that help the body use this boost the right way. When nitric oxide increases, your body needs support to move that benefit to the brain, heart, and cells. That’s where the other ingredients in CircO2® step in.
One of those ingredients is vitamin B12. But this vitamin helps cells respond to nitric oxide. It supportively better energy, strong focus, and proper nerve signals. So, B12 plays a key role in helping the brain stay sharp. It also supports clear memory and steady thinking, especially as people grow older.
Then there are vitamin C, another important part of this formula. Vitamin C helps carry nitric oxide to different parts of the body. It also supportive tissue repair and it helps the build collagen, which is needed for skin, joints, and blood vessels but vitamin C also helps the body use calcium in the right way, which supports stronger bones and healthy aging.
Next comes magnesium, a very important mineral. Magnesium supports steady heartbeats and helps relax the blood vessel walls. It allows blood to flow without pressure. It also keeps calcium from piling up in the arteries, which supports clean, open blood paths, that magnesium helps with muscle movement and relaxation as well, which adds to overall comfort and sleep quality.
CircO2® brings all these nutrients together with its nitric oxide blend to give the body full support. These extra nutrients work in balance to help your heart, brain, and blood flow respond better to nitric oxide. This balanced formula gives more than just a short-term boost—it supports whole-body wellness in the long run.
There’s also one more unique part of CircO2®.
This is the only nitric oxide product available that shows you real-time results. It comes with an easy nitric oxide test strip that lets you see the difference for yourself. You don’t need a lab or blood test. You just use the strip to check your nitric oxide level before and after use. This shows you how well your body is making and using nitric oxide from the supplement.
Most products give no way to see results. CircO2® is different. It gives support and also shows you that it works.
“Down to the Last Lozenge Guarantee”
You can try CircO2® with complete confidence. It comes with a clear and simple 90-day promise.
If CircO2® does not feel right for you, or if you think it does not support your health in the way you expect, you can send it back. It does not matter how much you have used. One dose or almost the full supply — no problem. You can still ask for your full refund.
Just return what you have left within 90 days from your purchase date. Once we receive it, we will give you all your money back. That means the full amount you paid, including any shipping or handling charges. You only cover the return postage.
This gives you plenty of time to try CircO2® and see how it works for you. If you feel it supports better blood flow, sharper memory, easier breathing, or steady energy, then you keep enjoying the benefits. If not, send it back. Simple.
This way, you get to try the product with zero risk and no pressure. You decide if CircO2® is right for you.
9 Ways We Guarantee the High Quality of
Advanced Bionutritionals Supplements
- Many nutritional products fail to pass important lab checks. That may happen when companies skip steps or use low-quality ingredients. But that does not happen here. We follow a system to keep quality and safety high from start to finish.
- We get our herbs, vitamins, and plant extracts from trusted sources. These suppliers work with us for many years. They give us materials that meet our standards.
- Only ingredients with support from scientific research are used. Every batch of raw material goes through tests. These tests check for things like mold, yeast, and bacteria such as salmonella and staph. If anything fails, it does not go into production.
- Our ingredients do not include fake colors, binders, or fillers. Artificial preservatives are avoided. We also choose non-GMO sources when they are available.
- Each sample is tested with modern lab tools like FTIR spectrometers. These machines check the material against a known purity standard. This confirms the identity and quality of every ingredient.
- Our supplements are made in a place that follows GMP — this stands for Good Manufacturing Practices. This means rules are followed to make safe, clean, and reliable products.
- Every batch is tested to see if it breaks down correctly after you swallow it. This is called a disintegration test. It checks that nutrients are released and absorbed the right way in your body. These steps follow guidelines set by USP.
- From start to end, the whole process has several quality checks. At each stage, trained people review the work. Before anything is packed, a quality control expert must approve the batch.
- Once the product is ready, it goes into safety-sealed bottles. These seals help protect freshness and strength. Each bottle has a clear label with either the date it was made or the date it expires.
Measure the Difference… Feel the Difference …Or You Pay Nothing
You can try CircO2® and check how it works for you. There is a simple way to test it. Measure your nitric oxide levels before you start. Then, use CircO2® every day and check your levels again after a few days. Notice how your body feels. Look at your energy, focus and how your body moves.
If you do not feel satisfied, or if you feel it is not giving you what you need, you can return it. Send back the unused part any time within 90 days. You will get all your money back. The full amount. No questions. You only cover the return shipping.
To help your body keep making nitric oxide daily, it makes sense to order more than one bottle. The best choice is the 3-month supply. You save money and get free shipping too. You receive enough CircO2® to last 90 days. This package gives you a discount of $15 off the price of buying single bottles one by one.
Or, for even more savings, go with the 6-month supply. This option gives you the biggest value. You get a total discount of $50.70 when compared to the single bottle price. You also receive free shipping with this offer.
